References / paperNodal signalling is involved in left–right asymmetry in snails
Grande, C.; Patel, N.H.
Year2009
Source roleprimary-study
DOI / ID10.1038/nature07603
Fitness and scope
event-mechanism · morphology · methods
Lottia and Biomphalaria embryos show opposite-sided nodal and Pitx expression, and pharmacological inhibition links the pathway to shell chirality in the sampled gastropods.
Claim ledger
event-mechanism · highIn Lottia gigantea and Biomphalaria glabrata embryos, nodal and Pitx expression occurs on opposite sides corresponding to adult chirality, and Nodal-pathway inhibition disrupts Pitx expression and shell coiling in the sampled system.
claim:event:gastropod-nodal-chirality