在巨帽贝 Lottia gigantea 和光滑双脐螺 Biomphalaria glabrata 的胚胎中，nodal 与 Pitx 在与成体手性相应的相反侧表达；抑制 Nodal 通路会扰乱该取样系统的 Pitx 表达和壳旋卷。
claim:event:gastropod-nodal-chiralityNodal signalling is involved in left–right asymmetry in snails
Grande, C.; Patel, N.H.
年份2009
来源角色primary-study
DOI / ID10.1038/nature07603
适用范围
event-mechanism · 形态 · methods
Lottia and Biomphalaria embryos show opposite-sided nodal and Pitx expression, and pharmacological inhibition links the pathway to shell chirality in the sampled gastropods.